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Turkish Journal of Medical Sciences

DOI

10.3906/sag-1712-28

Abstract

Background/aim: Vitamin D deficiency in diabetic patients has been shown to be associated with some in ammatory markers. However, its relationship with erythrocyte sedimentation rate (ESR) is still unknown. The aim of this study was to investigate the relationship between vitamin D deficiency and ESR in patients with type 2 diabetes mellitus (T2DM). Materials and methods: This cross-sectional study was conducted with 294 consecutive patients with T2DM. Serum levels of 25-hydroxyvitamin D, glycemic parameters, lipids, ESR, and C-reactive protein were measured. Patients were evaluated according to 25-hydroxyvitamin D levels as having vitamin D deficiency, vitamin D insuficiency, and vitamin D su ciency. Results: ESR was found to be higher in patients with vitamin D de ciency than in patients who were vitamin D-su cient (P < 0.001), and ESR was negatively correlated with 25-hydroxyvitamin D level (r = ?0.265, P < 0.001). HbA1c and postprandial glucose levels were higher in patients with vitamin D de ciency than vitamin D-suficient patients (P = 0.005 and P = 0.019, respectively). In receiver operating curve analysis, an ESR value of 14.5 mm/h had 70.1% sensitivity and 50.3% speci city for the prediction of vitamin D deficiency. Conclusion: The present study revealed that ESR is higher in T2DM patients with vitamin D de ciency than patients with suficient vitamin D. There was an inverse association between ESR and vitamin D levels. Furthermore, vitamin D deficiency was related to poor glycemic control.

Keywords

Blood sugar, dyslipidemia, HbA1c protein, inflammation

First Page

424

Last Page

429

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