Turkish Journal of Medical Sciences




Background/aim: We investigated whether obstructive sleep apnea syndrome (OSAS) has any impact on pulmonary artery distensibility (PAD) and right ventricular (RV) function. Materials and methods: Subjects were categorized according to apnea?hypopnea index (AHI) as follows: controls (n = 17 and AHI < 5), mild-to-moderate OSAS (n = 22 and AHI = 5?30), and severe OSAS (n = 29 and AHI > 30). All subjects underwent transthoracic echocardiography a er polysomnography to assess PAD and RV function. PAD was recorded as M-Mode trace of the right pulmonary artery and was de ned as (PAmax ?PAmin/PAmin) × 100. S? was measured by means of TDI of the lateral annulus of the RV using apical four-chamber view. Results: Patients with severe OSAS demonstrated impaired RV longitudinal systolic function (S?) compared to the other groups (P < 0.05). Impaired pulmonary vasculature elastic properties as re ected by decreased PAD were more prevalent in severe OSAS (26.2 < 5.7%) compared to the controls (29.9 ± 4.6%; P < 0.05) and mild-to-moderate OSAS (29.0 ± 4.1%; P < 0.05). An inverse relation between PAD (P < 0.05), RV myocardial performance index (MPI) (P < 0.05), and AHI was demonstrated. S? also correlated with PAD (P < 0.05). Conclusion: PAD is a signi cant tool to evaluate pulmonary vasculature sti ening and is well correlated with disease severity in OSAS. Further, impaired PAD may lead to RV systolic dysfunction.


Echocardiography, obstructive sleep apnea syndrome, pulmonary artery distensibility, apnea?hypopnea index, myocardial performance index

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