Turkish Journal of Medical Sciences
DOI
10.3906/sag-1709-46
Abstract
Background/aim: The prognostic value of the red cell distribution width (RDW) as a cost-effective and noninvasive test in acute pulmonary embolism (PE) is still unknown. We aimed to investigate the prognostic value of the admission RDW level in the long-term survival of PE patients. Materials and methods: In this registry-based, prospective cohort study, a total of 378 patients (mean age: 60.4 ± 17.11 years, 47.4% female) who presented with acute PE were enrolled. All the clinical data for each patient were obtained from our institutional PE registry. The follow-up was performed at a median time of 17 months. e primary endpoint was death at follow-up. Results: The mean RDW in study patients was 14.67 ± 2.13. e all-cause mortality rate during the follow-up was 15.6% (n = 59). A er adjustment for potential confounders, the relationship between RDW and long-term mortality showed a trend of a signi cant level (hazard ratio: 1.109; 95% CI, 0.998?1.232; P = 0.053). We divided patients into 3 groups based on the European Society of Cardiology?s classi cation. As we moved from the low risk to the higher risk categories, the mean RDW increased signi cantly (P = 0.037). Conclusion: It seems there may be an independent association between RDW at presentation and PE mortality within 17 months.
Keywords
Pulmonary embolism, red cell distribution width, mortality
First Page
318
Last Page
323
Recommended Citation
KHEIRKHAH-SABETGHADAM, SHAHRBANOO; JENAB, YASER; HEFZABAD, SEYED MOHAMMAD GHOREYSHI-; GOHARI-MOGHADAM, KEYVAN; LOTFI-TOKALDANY, MASOUMEH; JALALI, ARASH; POURJAFARI, MARZIEH; SHIRANI, SHAPOUR; ANVARI, MARYAM SOTOUDEH; and ETESAMIFAR, NASRIN
(2018)
"Association between elevated red blood cell distribution width and long-term mortality in acute pulmonary embolism,"
Turkish Journal of Medical Sciences: Vol. 48:
No.
2, Article 17.
https://doi.org/10.3906/sag-1709-46
Available at:
https://journals.tubitak.gov.tr/medical/vol48/iss2/17