Age-related macular degeneration and Alzheimer disease

Authors

EREN ÇERMAN
MUHSİN ERASLAN
OSMAN ÇEKİÇ

DOI

10.3906/sag-1406-146

Abstract

This review highlight the similarities in the pathogenesis between Alzheimer disease and age-related macular degeneration. All studies published between 1990 and 2014 were reviewed to identify the common pathological pathways. Alzheimer disease and age-related macular degeneration share common features such as vitronectin and amyloid-β accumulation, increased oxidative stress, and apolipoprotein and complement activation pathways, which are reviewed as histologic and immunologic common features.

First Page

1004

Last Page

1009

Recommended Citation

ÇERMAN, EREN; ERASLAN, MUHSİN; and ÇEKİÇ, OSMAN (2015) "Age-related macular degeneration and Alzheimer disease," Turkish Journal of Medical Sciences: Vol. 45: No. 5, Article 3. https://doi.org/10.3906/sag-1406-146
Available at: https://journals.tubitak.gov.tr/medical/vol45/iss5/3