Turkish Journal of Medical Sciences
Optimizing individual treatment outcomes in men with lower urinary tract symptoms using storage subscale score/total International Prostate Symptom Score (IPSS) as a new IPSS ratio
To evaluate the effects of the storage/total International Prostate Symptom Score (s/T) ratio on the selection and success of medical therapy in men with lower urinary tract symptoms (LUTS). Materials and methods: A total of 54 men (>45 years of age) with moderate or severe LUTS were divided into 2 groups according to the s/T ratio: Group 1 at 0.43. Tamsulosin (0.4 mg to Group 1) and tolterodine ER (4 mg to Group 2) were administered. Patients were evaluated during the 1st and 3rd months of follow-up treatment. Results: Thirty-seven (68.5%) and 17 (31.5%) patients were in Groups 1 and 2, respectively. The mean s/T ratios in Groups 1 and 2 increased to 0.38 ± 0.19 from 0.33 ± 0.08 (P = 0.03) and decreased to 0.54 ± 0.18 from 0.59 ± 0.1 (P = 0.17) during the 3rd month of follow-up, respectively. The treatment success rates of Groups 1 and 2 were 88.4% and 75.7%, respectively. Nine unsuccessful cases were treated with combination therapy and the treatment success was 86.6% at follow-up. Conclusion: The s/T ratio is effective to determine symptom dominance in men with LUTS and can guide medical treatment selection through better identification of symptoms.
Lower urinary tract symptoms, medical therapy, storage symptoms, antimuscarinics, alpha-blockers, treatment success, International Prostate Symptom Score
ALTINTAS, SERKAN; ACAR, İSMAİL CENK; ESKİÇORAPÇI, SAADETTİN YILMAZ; ZÜMRÜTBAŞ, ALİ ERSİN; BOLAT, DENİZ; TUNCAY, ÖMER LEVENT; and SINIK, MEHMET ZAFER
"Optimizing individual treatment outcomes in men with lower urinary tract symptoms using storage subscale score/total International Prostate Symptom Score (IPSS) as a new IPSS ratio,"
Turkish Journal of Medical Sciences: Vol. 44:
6, Article 33.
Available at: https://journals.tubitak.gov.tr/medical/vol44/iss6/33