Association between maternal ghrelin levels and hyperemesis gravidarum

Authors

İKBAL KAYGUSUZ
İLKNUR İNEGÖL GÜMÜŞ
MELAHAT YILDIRIM
HÜSAMETTİN ERDAMAR
AYSEL UYSAL
SERAP AYNUR SİMAVLI
ABDULLAH AYYILDIZ
MUHAMMET RAMAZAN YİĞİTOĞLU

DOI

10.3906/sag-1209-9

Abstract

To investigate serum levels of ghrelin in pregnant women as a potential early marker for hyperemesis gravidarum (HG). Materials and methods: A cross-sectional study was carried out at Fatih University Hospital. Included in the study were 35 women with HG and 31 pregnant women without HG as a control group. The groups were compared in terms of age, gravidity, body mass index (BMI), and fasting serum thyroid-stimulating hormone (TSH) and ghrelin levels. Results: Ghrelin levels of the patients with HG were found to be significantly lower than those in the control group (P = 0.03). No intergroup differences could be found in serum TSH or BMI values . Conclusion: Ghrelin might serve as a reliable marker in the etiopathogenesis of HG.

Keywords

Hyperemesis gravidarum, pregnancy, ghrelin, etiopathogenesis, thyroid-stimulating hormone, body mass index

First Page

790

Last Page

794

Recommended Citation

KAYGUSUZ, İKBAL; GÜMÜŞ, İLKNUR İNEGÖL; YILDIRIM, MELAHAT; ERDAMAR, HÜSAMETTİN; UYSAL, AYSEL; SİMAVLI, SERAP AYNUR; AYYILDIZ, ABDULLAH; and YİĞİTOĞLU, MUHAMMET RAMAZAN (2013) "Association between maternal ghrelin levels and hyperemesis gravidarum," Turkish Journal of Medical Sciences: Vol. 43: No. 5, Article 19. https://doi.org/10.3906/sag-1209-9
Available at: https://journals.tubitak.gov.tr/medical/vol43/iss5/19