To investigate the serum AMH and various biochemical parameter levels in patients with cryptorchidism, oligospermia, or varicocele. Materials and methods: This study included 100 participants, divided into 5 groups: cryptorchidism (n = 20), varicocele (n = 20), oligospermia (n = 20), and 2 control groups [control 1, 8-12 years old (n = 20) and control 2, 18-24 years old (n= 20)]. Using the blood samples drawn from both patient and control groups, AMH, testosterone, FSH, LH, and prolactin parameters were investigated. Results: AMH values measured were found to be 73.04 ± 44.5 ng/mL and 84.81 ± 59.1 ng/mL in 20 children with cryptorchidism and 20 healthy children (both groups aged between 8 and 12 years), respectively (P = 0.56). In the present study, AMH values were found to be 5.19 ± 4.9 ng/mL and 7.66 ± 5.6 ng/mL in 20 patients with oligospermia and 20 healthy individuals (both groups aged between 18 and 24 years), respectively (P = 0.10). AMH values in 20 patients with varicocele and 20 healthy controls aged between 18 and 24 years were determined to be 7.15 ± 5.8 ng/mL and 7.66 ± 5.6 ng/mL, respectively (P = 0.82). No significant P values were determined, but the decrease in values was remarkable. Conclusion: New studies with larger number of participants are needed in order to determinate AMH levels in patients with varicocele, cryptorchidism, or varicocele for diagnostic criteria.
Anti-Müllerian hormone, varicocele, infertility, cryptorchidism
AKDAĞ, TURAN; TİFTİK, ALİ MUHTAR; and SARIYILDIZ, LEVENT
"A comparative investigation of anti-Müllerian hormone (AMH) and various biochemical parameters in patients with cryptorchidism, oligospermia, or varicocele*,"
Turkish Journal of Medical Sciences: Vol. 42:
3, Article 6.
Available at: https://journals.tubitak.gov.tr/medical/vol42/iss3/6