Turkish Journal of Medical Sciences




Urodynamic studies have been associated with an increased risk of bacteriuria and symptomatic urinary tract infection (UTI) because it is applied by invasive catheterization. In this study the value of antibiotic prophylaxis in decreasing the risk of bacteriuria and symptomatic UTI has been questioned in children. Materials and methods: Urine samples of 90 patients, who were taken before and after urodynamic testing in Cerrahpaşa Faculty of Medicine Videourodynamics Laboratory of Child Surgery Department, were cultured microbiologically to determine the presence of bacteriuria. Results: The rate of bacteriuria was found statistically higher in 50 patients under trimethoprim/sulphamethoxazole and 17 under nitrofurantoin prophylaxis after the urodynamics (P < 0.05) compared to pre-urodynamics. According to our results, the most frequently bacteria detected before urodynamic testing was E. coli (in 25 patients, 3 of them ESBL + strains) as it was the same as post-urodynamics. Conclusion: As a result, we suggest that it will be necessary to evaluate prophylactic usage of trimethoprim-sulfamethoxazole and nitrofurantoin. The isolation of some nosocomial infectious agents is considered as another significant point of our study. ESBL + E. coli and Enterococcus faecium strains, which were isolated from patients under prophylaxis, showed the importance of this kind of surveillance studies.

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