The effects of cigarette smoking on serum oxidant status, and cholesterol, homocysteine, folic acid, copper, and zinc levels in university students

Authors

İMGE B. ERGÜDER
ASLI UÇAR
IŞIL ARITÜRK
TOKER ERGÜDER
ASLIHAN AVCI
SENİHA HASİPEK
KADİRHAN SUNGUROĞLU

DOI

10.3906/sag-0805-41

Abstract

Aim: To examine the effect of cigarette smoking on serum oxidative damage and oxidant status in university students. Materials and Methods: Subjects were randomly chosen from among Ankara University Faculty of Science students. The study was performed at the Ankara University Faculty of Health Sciences, Department of Nutrition and Dietetics, and the Ankara University Faculty of Medicine, Department of Biochemistry. In all, 44 volunteer (22 smokers and 22 non-smokers) students participated in the study. Malondialdehyde, sensitivity to oxidation (SO), and antioxidant potential (AOP), and total cholesterol, HDL cholesterol, LDL cholesterol, VLDL cholesterol, homocysteine, folic acid, copper, and zinc levels were measured in serum samples. Results: Serum SO levels were significantly higher in smokers than in non-smokers (1.01 ± 0.64 and 0.49 ± 0.14, respectively). Conclusions: Smoking history could be evidence of oxidative stress (high serum SO concentrations) and an impaired oxidant defense system.

Keywords

Smoking, sensitivity to oxidation, antioxidant potential, cholesterol, homocysteine, folic acid, copper, zinc

First Page

513

Last Page

517

Recommended Citation

ERGÜDER, İMGE B.; UÇAR, ASLI; ARITÜRK, IŞIL; ERGÜDER, TOKER; AVCI, ASLIHAN; HASİPEK, SENİHA; and SUNGUROĞLU, KADİRHAN (2009) "The effects of cigarette smoking on serum oxidant status, and cholesterol, homocysteine, folic acid, copper, and zinc levels in university students," Turkish Journal of Medical Sciences: Vol. 39: No. 4, Article 3. https://doi.org/10.3906/sag-0805-41
Available at: https://journals.tubitak.gov.tr/medical/vol39/iss4/3