Turkish Journal of Medical Sciences
Radiological and pathological correlation in patients with bronchioloalveolar lung carcinoma
Aim: To assess the correlation between pathological and radiological findings in patients with pure bronchioloalveolar carcinoma (BAC). Materials and Methods: We retrospectively evaluated the pathological and radiological findings in patients with pure BAC. Results: We reviewed the case records, pathological specimens, and computer files of 26 patients with a pathologic diagnosis of pure BAC during a 3-year period. There was a statistically significant relationship between pathological and radiological findings (X^2 = 15.143, P = 0.004). There was a correlation between mucinous pathology and diffuse pattern, as well as between non-mucinous pathology and solitary nodule/mass/cavitation. A statistically significant relationship between lymphocytic infiltration of the tumor and radiological findings was not observed (X^2 = 10.057, P = 0.122). A statistically significant relationship between the presence of sclerosis and radiological findings was observed (X^2 = 6.229, P = 0.044). In the presence of sclerosis, solitary nodule/ mass/cavitation radiological findings were seen more frequently. Conclusions: A diffuse radiological pattern was correlated with BAC mucinous subtype, while solitary nodule/mass/cavitation was correlated with non-mucinous pathology and the presence of sclerosis; however, we could not define a 100% relationship between them. In order to understand the biological nature of the disease, additional molecular and genetic studies are required.
Lung cancer, radiology of lung cancer, pathology of lung cancer, bronchioloalveolar carcinoma.
ÖCAL, SERPİL; ÜÇOLUK, GÜLNUR ÖNDE; SAMURKAŞOĞLU, BELGİN; DEMİRAĞ, FUNDA; ETİKAN, İLKER; and BAYAZIT, PELİN
"Radiological and pathological correlation in patients with bronchioloalveolar lung carcinoma,"
Turkish Journal of Medical Sciences: Vol. 39:
4, Article 11.
Available at: https://journals.tubitak.gov.tr/medical/vol39/iss4/11