Turkish Journal of Medical Sciences
Malignant infantile osteopetrosis (MIOP) is a rare inherited bone disease characterized by reduced or dysregulated activity of osteoclasts, which results in generalized osteosclerosis. This leads to abnormal bone marrow cavity formation and to the clinical signs and symptoms of bone marrow failure and nerve compression. Symptoms related to early or late hypocalcemia may appear as the first presentation of MIOP in a newborn. We present a 14-day-old boy with neonatal hypocalcaemia due to MIOP.
Malignant infantile osteopetrosis, neonatal hypocalcaemia
UZUN, HAKAN; KESKİN, EBRU YILMAZ; ŞENSES, DURSUN ALİ; ERDEM, AYHAN; DİKİCİ, BÜNYAMİN; and KOCABAY, KENAN
"A rare cause of neonatal hypocalcemia: malignant infantile osteopetrosis,"
Turkish Journal of Medical Sciences: Vol. 39:
3, Article 17.
Available at: https://journals.tubitak.gov.tr/medical/vol39/iss3/17