Aims: To determine viral causes of acute upper respiratory tract infections and clinical findings in children living in Istanbul, Turkey. Materials and Methods: This prospective study was carried out in 234 outpatient children (age range: 1-180 months) with acute upper respiratory tract infections, seen in the outpatient clinic at Istanbul Medical School Children´s Hospital. After clinical findings were recorded, nasal swab specimens were taken. In 201 specimens collected, influenza-A and -B, adenovirus, respiratory syncytial virus, and parainfluenza viruses were studied using direct fluorescence antibody, polymerase chain reaction (PCR), and cell culture techniques. Results: Rate of virus isolation was 29.8% (60/201). The viruses isolated in decreasing order were influenza-A (36.6%), adenovirus (28.4%), parainfluenza (14.9%), and respiratory syncytial virus (13.5%). All influenza-A cases were type H3N2. The common viruses in children less than 2 years of age were respiratory syncytial virus (63%) and adenovirus (59%), whereas influenza-A was dominant over 2 years of age (82%). Clinical symptoms did not differ among the different viral causes. Conclusions: Viral etiologies in children with acute upper respiratory tract infections were shown at a rate of 29.8% and the most common causes were influenza-A, adenovirus and parainfluenza viruses.
Child, infection, respiratory, viral
ÜNÜVAR, EMİN; YILDIZ, İSMAİL; KILIÇ, AYŞE; ASLAN, SEYHAN SELVİ; ÇAKAL, BÜLENT; TOPRAK, SADIK; BADUR, SELİM; OĞUZ, FATMA; and SIDAL, MÜJGAN
"Viral Etiology and Symptoms of Acute Upper Respiratory Tract Infections in Children,"
Turkish Journal of Medical Sciences: Vol. 39:
1, Article 5.
Available at: https://journals.tubitak.gov.tr/medical/vol39/iss1/5