Aim: Electrocautery has been postulated as a risk factor for wound complications. This study was conducted to evaluate the effects of electrocautery and scalpel dissections on wound complications and local cytokine levels. Materials and Methods: Patients undergoing modified radical mastectomy were assigned to flap dissection with either electrocautery (n = 18) or scalpel (n = 20). Blood loss, drain volume and duration, seroma formation and wound complications were recorded. Tumor necrosis factor-alpha (TNF-\alpha) and interleukin (IL)-6 levels were measured in drain fluids at postoperative 24 hours. Results: The electrocautery group had significantly reduced blood loss and total drain volume, but increased seroma formation rate. Significantly elevated levels of TNF-a\alpha were measured in drain fluids of patients with electrocautery dissection. Conclusions: The use of electrocautery causes less bleeding and total drain output with an increased rate of seroma formation. Electrocautery dissection increases pro-inflammatory cytokine response in wound fluid, which may reflect an aggravated inflammation and increased potential for tissue damage.
ÖZDOĞAN, MEHMET; YILMAZ, KERİM BORA; ÖZASLAN, CİHANGİR; GÜRER, AHMET; GÜLBAHAR, ÖZLEM; and ERSOY, EREN (2008) "Scalpel Versus Electrocautery Dissections: The Effect on Wound Complications and Pro-Inflammatory Cytokine Levels in Wound Fluid," Turkish Journal of Medical Sciences: Vol. 38: No. 2, Article 3. Available at: https://journals.tubitak.gov.tr/medical/vol38/iss2/3