In Vitro Testing for Genotoxicity of 4-CPA by Sister Chromatid Exchange in Human Lymphocyte Culture

Authors

HÜSEYİN BAĞCI
GÜLSEREN BAĞCI
İBRAHİM AÇIKBAŞ
GÖKSEMİN DEMİR

Abstract

Certain phenoxyacetate derivatives used as plant growth regulators act as plant hormones. 2,4-D dichlorophenoxyacetic acid and 4-chlorophenoxyacetic acid are widely used in vegetable growing, especially tomatoes, in our region. These phenoxyacetic acid compounds are a potential hazard for the environment. There are conflicting results and inconsistent data about these herbicides in the literature. This is the first report of genotoxicity of 4-CPA evaluated by sister chromatid exchange in human lymphocyte culture. No significant change was found in sister chromatid exchange frequency at the tested 4-CPA concentration.

DOI

-

Keywords

4-CPA, Phenoxy herbicides, genotoxicity, sister chromatid exchange, tomato

First Page

75

Last Page

78

Recommended Citation

BAĞCI, H, BAĞCI, G, AÇIKBAŞ, İ, & DEMİR, G (2005). In Vitro Testing for Genotoxicity of 4-CPA by Sister Chromatid Exchange in Human Lymphocyte Culture. Turkish Journal of Medical Sciences 35 (2): 75-78. https://doi.org/-