Turkish Journal of Medical Sciences
Abstract
We aimed to assess chromosomal aberration frequency by means of FISH chromosome painting and conventional Giemsa staining in peripheral blood lymphocytes of workers at a nuclear waste repository. The results obtained from the exposed group were compared with those from a control group from the administrative staff of the company. Data on health and social status were collected using a questionnaire. Conventional chromosomal analysis after Giemsa staining did not indicate any significant difference between radiation exposed and control workers. Analysis after FISH chromosome painting revealed a 2-fold increased in genomic frequency of stable chromosomal translocations in the exposed group over the control group. The difference is of marginal statistical significance.
DOI
-
Keywords
Occupational radiation exposure, Human lymphocytes, Chromosomal aberrations, Fluorescent in situ hybridization
First Page
359
Last Page
365
Recommended Citation
ATANASOVA, PETYA; HADJIDEKOVA, VALERIA BORISOVA; AGOVA, SAVINA; and IOVTCHEV, MILEN (2004) "Chromosomal Aberrations in Radiation Waste Repository Workers Detected by Fish Painting and Giemsa Staining," Turkish Journal of Medical Sciences: Vol. 34: No. 6, Article 1. Available at: https://journals.tubitak.gov.tr/medical/vol34/iss6/1
