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Turkish Journal of Medical Sciences

DOI

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Abstract

Gene therapy, being a novel treatment for many diseases, is readily applicable for the treatment of cancer patients. Breast cancer is the most common cancer among women. There are many clinical protocols for the treatment of breast cancer, and gene therapy is now being considered within current protocols. This review will focus on the basic concepts of cancer gene therapy strategies (suicide gene, tumor suppressor gene, anti-angiogenesis, immunotherapy, oncolytic viruses and ribozyme/antisense targeting) and current approaches for breast cancer gene therapies.

Keywords

gene therapy, breast cancer, viral vectors, vector targeting

First Page

283

Last Page

291

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