Thymidine Labeling Index in Laryngeal Squamous Cell Carcinoma

Authors

MURAT ÜNAL
AYHAN BİLİR
MESUT CAN KARATAY
İSMAİL ÇÖLHAN

DOI

-

Abstract

The aim of this study was to investigate the prognostic value of the thymidine labeling index (TLI) in laryngeal squamous cell carcinoma (SCC). The TLI in tumor tissue and adjacent healthy tissue was assessed prospectively in 31 patients and these values were correlated with age, TNM, grade and recurrence statistically. The tissues (tumoral and adjacent tumor-free tissue) that were obtained during surgery were labeled with ^3H-Thymidine. TLI was calculated as the number of labeled tumor cells * 100 / total number of tumor cells. A statistically significant difference was observed between tumor tissue (mean TLI value = 17.62± 6.39%) and adjacent tumor-free tissue (mean TLI value = 9.16±3.32%) (p

Keywords

Thymidine labeling index, laryngeal squamous cell carcinoma, prognostic factors

First Page

139

Last Page

143

Recommended Citation

ÜNAL, MURAT; BİLİR, AYHAN; KARATAY, MESUT CAN; and ÇÖLHAN, İSMAİL (2002) "Thymidine Labeling Index in Laryngeal Squamous Cell Carcinoma," Turkish Journal of Medical Sciences: Vol. 32: No. 2, Article 9. Available at: https://journals.tubitak.gov.tr/medical/vol32/iss2/9