Antifungal Activities of Different Extracts and Echimidine-N-oxide from Symphytum sylvaticum Boiss. subsp. sepulcrale (Boiss. & Bal.) Greuter & Burdet var. Sepulcrale

Authors

MURAT KARTAL
SEMRA KURUCU
MUHAMMAD I. CHOUDARY

Abstract

Antifungal activity was determined by the tube dilution method on different extracts of Symphytum sylvaticum Boiss. subsp. sepulcrale (Boiss. & Bal.) Greuter & Burdet var. sepulcrale. The antifungal activity of the isolated compound from the root alkaloid fraction (Echimidine-N-Oxide) was also tested against ten fungal cultures. The activity was found to be mainly due to Echimidine-N-Oxide (ENO). The quantitative determination of ENO was also carried out with capillary gas chromatography in the roots and the aerial parts of the plant.

DOI

-

Keywords

Symphytum sylvaticum, pyrrolizidine alkaloids, echimidine-N-oxide, antifungal activity, GC analysis

First Page

487

Last Page

492

Recommended Citation

KARTAL, MURAT; KURUCU, SEMRA; and CHOUDARY, MUHAMMAD I. (2001) "Antifungal Activities of Different Extracts and Echimidine-N-oxide from Symphytum sylvaticum Boiss. subsp. sepulcrale (Boiss. & Bal.) Greuter & Burdet var. Sepulcrale," Turkish Journal of Medical Sciences: Vol. 31: No. 6, Article 4. Available at: https://journals.tubitak.gov.tr/medical/vol31/iss6/4