Turkish Journal of Medical Sciences
DOI
-
Abstract
Antifungal activity was determined by the tube dilution method on different extracts of Symphytum sylvaticum Boiss. subsp. sepulcrale (Boiss. & Bal.) Greuter & Burdet var. sepulcrale. The antifungal activity of the isolated compound from the root alkaloid fraction (Echimidine-N-Oxide) was also tested against ten fungal cultures. The activity was found to be mainly due to Echimidine-N-Oxide (ENO). The quantitative determination of ENO was also carried out with capillary gas chromatography in the roots and the aerial parts of the plant.
Keywords
Symphytum sylvaticum, pyrrolizidine alkaloids, echimidine-N-oxide, antifungal activity, GC analysis
First Page
487
Last Page
492
Recommended Citation
KARTAL, MURAT; KURUCU, SEMRA; and CHOUDARY, MUHAMMAD I. (2001) "Antifungal Activities of Different Extracts and Echimidine-N-oxide from Symphytum sylvaticum Boiss. subsp. sepulcrale (Boiss. & Bal.) Greuter & Burdet var. Sepulcrale," Turkish Journal of Medical Sciences: Vol. 31: No. 6, Article 4. Available at: https://journals.tubitak.gov.tr/medical/vol31/iss6/4
