Turkish Journal of Medical Sciences




Many risk factors for coronary heart disease (CHD) have been reported to date. Recently, it has been shown that elevations in homocysteine (Hcy) levels may contribute to the development of coronary heart diseases. In this study, our aim was to determine the relation of Hcy levels and other risk factors in CHD. Serum Hcy, lipoprotein(a) [Lp(a)], C-reactive protein (CRP), fibrinogen, cholesterol, triglyceride, HDL and LDL levels were measured in 51 male patients, diagnosed with CHD with negative T elevations in electrocardiograms, and in 20 healthy males. Hcy was determined in serum samples with Fluorescence Polarization Immunoassay (FPIA) on Abbott IMx. All the parameters were found to be significantly higher (p0.05), while CRP was well correlated with fibrinogen and Lp(a), and Lp(a) was well correlated with fibrinogen (p


atherosclerosis, homocysteine, fibrinogen, CRP, Lp(a)

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