Turkish Journal of Medical Sciences
DOI
-
Abstract
Objective: The purpose of the present study was to investigate the effects of the presence of hypersplenism, antiplatelet antibody and anticardiolipin antibody, which are thought to be important factors, on the development of thrombocytopenia in patients with cirrhosis with viral etiology. Methods: This study includes 44 patients with cirrhosis related to HBV and HCV, and 12 healthy control subjects. Spleen size was evaluated by ultrasonography, the presence of antiplatelet antibody by flow cytometry, and IgG and IgM isotypes of anticardiolipin anti- body by enzyme immunoassay. Results: There was a significant difference in ultrasonographic spleen size between the patients with and without thrombocytopenia (p
Keywords
Cirrhosis, thrombocytopenia, anticardiolipin antibody, antiplatelet antibody
First Page
589
Last Page
594
Recommended Citation
YAVUZ, HASAN; SARICAM, TÜLAY; GÜLBAŞ, ZAFER; ÖZAKYOL, AYŞEGÜL; VARDARELİ, ESER; and ERENOĞLU, ESAT (2000) "The Importance of Anticardiolipin Antibody and Antiplatelet Antibody in the Development of Thrombocytopenia in Cirrhosis," Turkish Journal of Medical Sciences: Vol. 30: No. 6, Article 13. Available at: https://journals.tubitak.gov.tr/medical/vol30/iss6/13
