Turkish Journal of Medical Sciences
DOI
-
Abstract
The present experimental study was carried out on rats subjected to ischemia and reperfusion. The effects of allopurinol on mucus, an important component of the stomach mucosal barrier, were investigated. Twenty-one Swiss Albino rats, each weighing 200-250 g, were used. On the control group, no treatment was performed, while the sham operation group was subjected to 30 minutes of ischemia and 20 minutes of reperfusion. Then, stomachs were examined for ulcerative lesions, and ulcer scores were recorded. Mucus content was determined by the Corne method. In the sham group, the mucus decreased to a significant extent (p
Keywords
Ischemia and reperfusion, stomach mucosal barrier, allopurinol
First Page
449
Last Page
452
Recommended Citation
ÖNEN, ABDURRAHMAN; KANAY, ZEKİ; GÜZEL, CİHAT; KURT, DOĞAN; and CEYLAN, KADER (2000) "The Effects of Allopurinol on Stomach Mucosal Barrier of Rats Subjected to Ischemia-Reperfusion," Turkish Journal of Medical Sciences: Vol. 30: No. 5, Article 7. Available at: https://journals.tubitak.gov.tr/medical/vol30/iss5/7
