Angiotensin converting enzyme (ACE) inhibitors have been known to inhibit the effects of angiotensin II which increases the vascular resistance. In this study, we studied the acute effects of a single dose of 2.5 mg oral cilazapril, ACE inhibitor on blood flow velocity and vascular resistance parameters of central retinal artery (CRA) by color Doppler ultrasonography in 17 patients with nonproliferative diabetic retinopathy (NPDR) and compared the effects of the drug with a placebo group including 17 patients with nonproliferative diabetic retinopathy. After cilazapril medication, peak systolic blood flow velocity of central retinal artery didn't change, while peak diastolic and mean blood flow velocity increased (p
Central retinal artery, diabetes retinopathy, cilazapril, color Doppler imaging.
ÇELEBİ, Serdal; ÇELİKER, Hüseyin; ÇELEBİ, Harika; and ÇELİKER, Ülkü Ö. (1998) "The Effects of ACE Inhibition on Central RetinalArtery in Diabetes Mellitus," Turkish Journal of Medical Sciences: Vol. 28: No. 6, Article 11. Available at: https://journals.tubitak.gov.tr/medical/vol28/iss6/11