Cryoglobulinemia has been reported rarely to cause false elevation in platelet and/or leukocyte counts due to temperature-dependent protein precipitates that interpreted as blood cells at room temperature. Upon heating to 37°C, these blood counts decrease to normal levels as cryoproteins dissolve. Here, we report two cases with this rare phenomenon that may lead to inappropriate investigations in clinical practice and have diagnostic significance when kept in mind.
Cryoglobulinemia, blood cell counts, pseudoleukocytosis, pseudothrombocytosis
İLERİ, Naciye Şemnur; BÜYÜKAŞIK, Yahya; KARAAHMETOĞLU, Selma; DEMİROĞLU, Halûk; MÜFTÜOĞLU, Osman; and DÜNDAR, Semra (1998) "Pseudoleukocytosis and Pseudothrombocytosis inCryoglobulinemia," Turkish Journal of Medical Sciences: Vol. 28: No. 3, Article 16. Available at: https://journals.tubitak.gov.tr/medical/vol28/iss3/16