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Turkish Journal of Medical Sciences

Article Title

The Effect of Systemic Angiotensin-Converting Enzyme Inhibition on Normal and Autonomous Functioning Lactotrophs

DOI

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Abstract

There are contradictory reports about the relation between pituitary local renin-angiotensin system (RAS) and the secretory functions of lactotrophs. We evaluated the effect of the ACE inhibitor captopril on plasma prolaction, growth hormone and TSH secretion in patients with idiopathic hyperprolactinemia (n= 18) and in hypertensive patients with normal pituitaries (n=12). A slight but significant fall in plasma prolaction levels at 60 (p

First Page

441

Last Page

445

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