Turkish Journal of Medical Sciences
Article Title
Urinary Albumin Excretion in Normal Subjects and in Diabetic Patients Measured by an Enzymeimmunoassay: Methodological and Clinical Aspects
DOI
-
Abstract
We have developed an enzymeimmunoassay (EIA) method to measure urinary albumin excretion. The albumin excretion rate (AER) (µg/min) of 93 healthy subjects and 116 diabetic patients (64 type l, 52 type ll) was determined. The validation results indicate that the EIA is a useful diagnostic tool. About 65 % of the diabetic patients lay within the normal range. The other 35% could be considered Òat riskÓ to develop overt diabetic nephropathy because their albuminuria exceeded a threshold level of 15 µg/min, chosen previously as the cutoff value for microalbuminuria. The AER of the normoalbuminuric type l and type ll diabetic patients was significantly higher than that of the controls (P
Keywords
Microalbuminuria, albumin excretion rate, diabetic nephropathy, diabetes mellitus, enzymeimmunoassay
First Page
237
Last Page
241
Recommended Citation
AKMAN, Şerif and KARACA, Levent (1996) "Urinary Albumin Excretion in Normal Subjects and in Diabetic Patients Measured by an Enzymeimmunoassay: Methodological and Clinical Aspects," Turkish Journal of Medical Sciences: Vol. 26: No. 3, Article 4. Available at: https://journals.tubitak.gov.tr/medical/vol26/iss3/4
