Turkish Journal of Medical Sciences

Plasma Lipid Peroxides, Vitamin E, Superoxide Dismutase and Glutathione Alterations in Coronary Atherosclerosis




The possible role of oxidant stress and antioxidant defense systems in the genesis of atherosclerosis is steadily gaining importance. From this point of view, plasma lipid peoxides (LP0), superoxide dismutase (Cu, Zn SOD), vitamin E and glutathione (GSH) levels were measured by colorimetry in 34 patients with coronary artery disease proved angiographically (7 patients with mild, 9 patients with moderate and 18 patients with severe coronary artery disease) and compared with 7 control subjects with normal coronary angiograms. Lipid peroxide concentrations were significantly higher in all three patient groups than controls (control: 1.35±0.41, mild: 1.82±0.33, moderate: 1.86±0.59 and severe: 2.55±0.72 nmol/ml, mean±SD, P


Lipid peroxides, vitamin E, Cu, Zn-superoxide dismutase, glutathione, coronary artery disease

First Page


Last Page


This document is currently not available here.