Turkish Journal of Chemistry
Abstract
In the present research, the aim was to develop a novel electrochemical enzyme-free glucose sensor dependent upon a nickel nanoparticles (NiNPs)/cobalt (II, III) oxide (Co3O4)/carboxylated graphene oxide (GO-COOH)-modified glassy carbon (GC) electrode. The electrocatalytic performance of the electrode was tested using various electrochemical methods such as amperometry and cyclic voltammetry (CV). The NiNPs@Co3O4/GO-COOH/GC electrode showed noticeably superior electrocatalytic behavior for glucose oxidation in 0.1 M NaOH media, ascribed to the good synergistic impact between NiNPs, Co3O4, and GO-COOH. The amperometric response of the NiNPs@Co3O4/GO-COOH/GC electrode to glucose exhibited two linear determination ranges at +0.55 V potential. The first one was between 4.8 × 10−7 and 9.5 × 10−4 M and the second one was between 9.5 × 10−4 and 4.87 × 10–3 M. The limit of detection was 1.4 × 10–7 M dependent upon a signal-to-noise ratio of 3. The sensor displayed good performance factors such as selectivity, reproducibility, and stability. Furthermore, the suitability of the sensor for detecting glucose in biological fluids proved satisfactory.
DOI
10.55730/1300-0527.3801
Keywords
Glucose, functionalized graphene oxide, NiNPs@Co3O4, sensor
First Page
327
Last Page
340
Publisher
The Scientific and Technological Research Council of Türkiye (TÜBİTAK)
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Recommended Citation
PEKMEZ, S, & GÜLER, M (2026). A nonenzymatic electrochemical glucose sensor depending on a NiNPs/Co3O4/functionalized graphene oxide-modified working electrode. Turkish Journal of Chemistry 50 (3): 327-340. https://doi.org/10.55730/1300-0527.3801
