Turkish Journal of Chemistry
Abstract
Injectable hydrogels play an important role in tissue engineering as a filling and repairing material. This study aimed to develop a new injectable hydrogel based on hyaluronic acid (HA) and quince seed gum (QSG) and investigate the effect of QSG on hydrogel performance. The amount of unreacted 1,4-Butanediol diglycidyl ether (BDDE) is maintained at an undetectable level for HA-QSG hydrogels. Amino acid analysis showed that the HA-QSG hydrogel had rich amino acid concentrations of leucine, arginine, and valine. After thermal sterilization, the elastic modulus of HA-QSG gels for dermal and intra-articular filler applications is 63 Pa and 92 Pa respectively. Pore size was found below 200 µm and the dense homogeneous pore structure was seen.
Author ORCID Identifier
ERDİNÇ BABUÇ: 0000-0001-7826-5357
GÖKAY GÜN: 0000-0002-4264-8273
NİLHAN KAYAMAN APOHAN: 0000-0002-7750-3058
SERDAR KOLAY: 0000-0002-2452-4197
DOI
10.55730/1300-0527.3669
Keywords
dermal filler injection, Hydrogel, intra-articular injection, quince seed gum, rheology
First Page
422
Last Page
435
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Recommended Citation
KOLAY, SERDAR; KAYAMAN APOHAN, NİLHAN; BABUÇ, ERDİNÇ; and GÜN, GÖKAY
(2024)
"Effect of quince seed gum (QSG) on the performance of injectable hyaluronic acid hydrogels in terms of the rheological, morphological, and mechanical aspect,"
Turkish Journal of Chemistry: Vol. 48:
No.
3, Article 2.
https://doi.org/10.55730/1300-0527.3669
Available at:
https://journals.tubitak.gov.tr/chem/vol48/iss3/2
