Turkish Journal of Chemistry

Author ORCID Identifier

ERDİNÇ BABUÇ: 0000-0001-7826-5357

GÖKAY GÜN: 0000-0002-4264-8273

NİLHAN KAYAMAN APOHAN: 0000-0002-7750-3058

SERDAR KOLAY: 0000-0002-2452-4197




Injectable hydrogels play an important role in tissue engineering as a filling and repairing material. This study aimed to develop a new injectable hydrogel based on hyaluronic acid (HA) and quince seed gum (QSG) and investigate the effect of QSG on hydrogel performance. The amount of unreacted 1,4-Butanediol diglycidyl ether (BDDE) is maintained at an undetectable level for HA-QSG hydrogels. Amino acid analysis showed that the HA-QSG hydrogel had rich amino acid concentrations of leucine, arginine, and valine. After thermal sterilization, the elastic modulus of HA-QSG gels for dermal and intra-articular filler applications is 63 Pa and 92 Pa respectively. Pore size was found below 200 µm and the dense homogeneous pore structure was seen.


dermal filler injection, Hydrogel, intra-articular injection, quince seed gum, rheology

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Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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