Turkish Journal of Chemistry
Abstract
Injectable hydrogels play an important role in tissue engineering as a filling and repairing material. This study aimed to develop a new injectable hydrogel based on hyaluronic acid (HA) and quince seed gum (QSG) and investigate the effect of QSG on hydrogel performance. The amount of unreacted 1,4-Butanediol diglycidyl ether (BDDE) is maintained at an undetectable level for HA-QSG hydrogels. Amino acid analysis showed that the HA-QSG hydrogel had rich amino acid concentrations of leucine, arginine, and valine. After thermal sterilization, the elastic modulus of HA-QSG gels for dermal and intra-articular filler applications is 63 Pa and 92 Pa respectively. Pore size was found below 200 µm and the dense homogeneous pore structure was seen.
Author ORCID Identifier
ERDİNÇ BABUÇ: 0000-0001-7826-5357
GÖKAY GÜN: 0000-0002-4264-8273
NİLHAN KAYAMAN APOHAN: 0000-0002-7750-3058
SERDAR KOLAY: 0000-0002-2452-4197
DOI
10.55730/1300-0527.3669
Keywords
dermal filler injection, Hydrogel, intra-articular injection, quince seed gum, rheology
First Page
422
Last Page
435
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Recommended Citation
KOLAY, S, KAYAMAN APOHAN, N, BABUÇ, E, & GÜN, G (2024). Effect of quince seed gum (QSG) on the performance of injectable hyaluronic acid hydrogels in terms of the rheological, morphological, and mechanical aspect. Turkish Journal of Chemistry 48 (3): 422-435. https://doi.org/10.55730/1300-0527.3669
