N-(2-Aminobenzoyl)benzotriazole Mediated Synthesis of 3- Acyl-2-alkyl(aryl)-4-hydroxyquinolines and 3-Acylamino-4(3H) quinazolinones

Authors

İlbilge Merve ŞENOLFollow
Sevtem Gökbulut SATIOĞLUFollow
İlhami ÇELİKFollow

DOI

10.55730/1300-0527.3642

Abstract

New methods have been developed for the synthesis of the substituted quinolines and quinazolinones derivatives by utilizing N-(2-aminobenzoyl)benzotriazoles under mild reaction conditions. 3-Acyl-2-alkyl(aryl)-4-hydroxyquinolines were obtained in modarete yields by the reaction of N-(2-aminobenzoyl)benzotriazoles and diketones in the presence of tert-BuOK. 3-Acylamino-4(3H) quinazolinones were obtained in good yields via N-(2-aminobenzoyl)benzotriazoles, orthoester and hyrazides in one-pot.

Keywords

Covid-19, N-(2-Aminobenzoyl)benzotriazoles, benzotriazole, quinoline, quinazolinone

First Page

97

Last Page

107

Recommended Citation

ŞENOL, İlbilge Merve; SATIOĞLU, Sevtem Gökbulut; and ÇELİK, İlhami (2024) "N-(2-Aminobenzoyl)benzotriazole Mediated Synthesis of 3- Acyl-2-alkyl(aryl)-4-hydroxyquinolines and 3-Acylamino-4(3H) quinazolinones," Turkish Journal of Chemistry: Vol. 48: No. 1, Article 9. https://doi.org/10.55730/1300-0527.3642
Available at: https://journals.tubitak.gov.tr/chem/vol48/iss1/9