N-(2-Aminobenzoyl)benzotriazole Mediated Synthesis of 3- Acyl-2-alkyl(aryl)-4-hydroxyquinolines and 3-Acylamino-4(3H) quinazolinones

Authors

İlbilge Merve ŞENOLFollow
Sevtem Gökbulut SATIOĞLUFollow
İlhami ÇELİKFollow

Abstract

New methods have been developed for the synthesis of the substituted quinolines and quinazolinones derivatives by utilizing N-(2-aminobenzoyl)benzotriazoles under mild reaction conditions. 3-Acyl-2-alkyl(aryl)-4-hydroxyquinolines were obtained in modarete yields by the reaction of N-(2-aminobenzoyl)benzotriazoles and diketones in the presence of tert-BuOK. 3-Acylamino-4(3H) quinazolinones were obtained in good yields via N-(2-aminobenzoyl)benzotriazoles, orthoester and hyrazides in one-pot.

DOI

10.55730/1300-0527.3642

Keywords

Covid-19, N-(2-Aminobenzoyl)benzotriazoles, benzotriazole, quinoline, quinazolinone

First Page

97

Last Page

107

Recommended Citation

ŞENOL, İ. M, SATIOĞLU, S. G, & ÇELİK, İ (2024). N-(2-Aminobenzoyl)benzotriazole Mediated Synthesis of 3- Acyl-2-alkyl(aryl)-4-hydroxyquinolines and 3-Acylamino-4(3H) quinazolinones. Turkish Journal of Chemistry 48 (1): 97-107. https://doi.org/10.55730/1300-0527.3642