Known 1,6-di(thiophen-2-yl)hexane-1,6-dione (2) and novel 1,7-di(thiophen-2-yl)heptane-1,7-dione (4) were obtained from the reactions of thiophene with the corresponding diacyl chlorides. Furthermore, compounds with furan and pyrrole units in place of thiophene units in compound 2 were obtained in the same way. Bromination of 2 and 4 gave bromides regioselectively. The reaction of each of the compounds 2 and 4 in HOAc medium yielded cyclocondensation products. In total, four known and eleven novel compounds were synthesized.
Acylation, bromination, cyclocondensation, diketone, thiophene
ARTUNÇ, TEKİN and MENZEK, ABDULLAH
"Synthesis and reactions of di(thiophen-2-yl)alkane diones: Cyclocondensation,"
Turkish Journal of Chemistry: Vol. 46:
5, Article 4.
Available at: https://journals.tubitak.gov.tr/chem/vol46/iss5/4