Synthesis and reactions of di(thiophen-2-yl)alkane diones: Cyclocondensation

Authors

TEKİN ARTUNÇ
ABDULLAH MENZEK

DOI

10.55730/1300-0527.3446

Abstract

Known 1,6-di(thiophen-2-yl)hexane-1,6-dione (2) and novel 1,7-di(thiophen-2-yl)heptane-1,7-dione (4) were obtained from the reactions of thiophene with the corresponding diacyl chlorides. Furthermore, compounds with furan and pyrrole units in place of thiophene units in compound 2 were obtained in the same way. Bromination of 2 and 4 gave bromides regioselectively. The reaction of each of the compounds 2 and 4 in HOAc medium yielded cyclocondensation products. In total, four known and eleven novel compounds were synthesized.

Keywords

Acylation, bromination, cyclocondensation, diketone, thiophene

First Page

1397

Last Page

1404

Recommended Citation

ARTUNÇ, TEKİN and MENZEK, ABDULLAH (2022) "Synthesis and reactions of di(thiophen-2-yl)alkane diones: Cyclocondensation," Turkish Journal of Chemistry: Vol. 46: No. 5, Article 4. https://doi.org/10.55730/1300-0527.3446
Available at: https://journals.tubitak.gov.tr/chem/vol46/iss5/4