Determination of characterization, antibacterial and drug release properties of POSS-based film synthesized with sol-gel technique

Authors

İDİL KARACA AÇARI
SÜLEYMAN KÖYTEPE
BURHAN ATEŞ
İSMET YILMAZ
TURGAY SEÇKİN

DOI

10.3906/kim-2101-56

Abstract

In the study, antibacterial film synthesis was aimed using sol-gel technique from POSS structure with various functional groups. For this purpose, antibacterial properties have been acquired by metronidazole to the films to be synthesized. The films obtained were coated on glass surface samples by dip coating method. Antibacterial activities of surface coated glass samples were observed in E.coli and S. aureus bacteria. Metronidazole release studies in the film samples were followed by UV spectrophotometer. It was observed that drug release reached 68.90% at the end of the 24th h. As a result, it is thought that the synthesized film will be a good candidate especially for biomedical surface coating areas.

Keywords

Polyhedral oligomeric silsesquioxane, dip coating, antibacterial activity, drug delivery

First Page

1774

Last Page

1785

Recommended Citation

AÇARI, İDİL KARACA; KÖYTEPE, SÜLEYMAN; ATEŞ, BURHAN; YILMAZ, İSMET; and SEÇKİN, TURGAY (2021) "Determination of characterization, antibacterial and drug release properties of POSS-based film synthesized with sol-gel technique," Turkish Journal of Chemistry: Vol. 45: No. 6, Article 9. https://doi.org/10.3906/kim-2101-56
Available at: https://journals.tubitak.gov.tr/chem/vol45/iss6/9