Turkish Journal of Chemistry
Novel vic-dioximes: synthesis, structure characterization, and antimicrobial activity evaluation
The vic-dioximes are compounds with various industrial uses and scientific applications. Many coordination compounds have been synthesized based on vic-dioximes. This study presents the synthesis and full characterization of two vic-dioximes based on dichloroglyoxime, p-aminobenzoic acid, and p-aminotoluene. Their structures were proved by IR, 1H, 13C and 15N NMR spectral analysis, and single crystal X-ray diffraction. One of the reported vic-dioximes, bis(di-p-aminotoluene)glyoxime mono-p-aminotoluene trihydrate showed good to moderate antimicrobial activity against both nonpathogenic gram-positive and gram-negative bacteria (Bacillus subtilis and Pseudomonas fluorescens), phytopathogenic (Xanthomonas campestris, Erwinia amylovora, E. carotovora) and the fungi (Candida utilis and Saccharomyces cerevisiae) at MIC - 70-150 μg/mL.
vic-dioxime, spectral analysis, X-ray diffraction, antibacterial activity, antifungal activity
URECHE, DUMITRU; BULHAC, ION; CIOCARLAN, ALEXANDRU; ROSHCA, DANIEL; LUPASCU, LUCIAN; and BOUROSH, PAULINA
"Novel vic-dioximes: synthesis, structure characterization, and antimicrobial activity evaluation,"
Turkish Journal of Chemistry: Vol. 45:
6, Article 18.
Available at: https://journals.tubitak.gov.tr/chem/vol45/iss6/18