Determination of blood glucose parameter from human blood serum by using a quartzcrystal microbalance sensor coated with phthalocyanines compounds

Authors

EVİN ŞAHİN SADIK
HAMDİ MELİH SARAOĞLU
İLKE GÜROL
MEHMET ALİ EBEOĞLU
FATMA EMEL KOÇAK

DOI

10.3906/kim-1911-69

Abstract

Determining the blood glucose level is important for the prevention and treatment of diabetes mellitus. We developed a sensor system using Quartz Crystal Microbalance (QCM) to determine the blood glucose level from human blood serum. This study consists of two experimental stages: artificial glucose/pure water solution tests and human blood serum tests. In the first stage of the study, the QCM sensor with the highest performance was identified using artificial glucose solution concentrations. In the second stage of the study, human blood serum measurements were performed using QCM to determine blood glucose levels. QCM sensors were coated with phthalocyanines (Pcs) by jet spray method. The blood glucose values of 96 volunteers, which ranged from 71 mg/dL to 329 mg/dL, were recorded. As a result of the study, human glucose values were determined with an average error of 3.25%.

Keywords

Phthalocyanines, blood glucose, human blood serum, liquid sensing, quartz crystal microbalance

First Page

1293

Last Page

1302

Recommended Citation

SADIK, EVİN ŞAHİN; SARAOĞLU, HAMDİ MELİH; GÜROL, İLKE; EBEOĞLU, MEHMET ALİ; and KOÇAK, FATMA EMEL (2020) "Determination of blood glucose parameter from human blood serum by using a quartzcrystal microbalance sensor coated with phthalocyanines compounds," Turkish Journal of Chemistry: Vol. 44: No. 5, Article 7. https://doi.org/10.3906/kim-1911-69
Available at: https://journals.tubitak.gov.tr/chem/vol44/iss5/7