Turkish Journal of Chemistry
Abstract
An amphiphilic core/shell-type polymer-based drug carrier system (HPAE- PCL-b-MPEG), composed of hyperbranched poly(aminoester)-based polymer (HPAE) as the core building block and poly(ethylene glycol)-bpoly(ε-caprolactone) diblock polymers (MPEG-b-PCL) as the shell building block, was designed. The synthesized polymers were characterized with FTIR, $^{1}$H NMR, $^{13}$C NMR, and GPC analysis. Monodisperse HPAE-PCL-bMPEG nanoparticles with dimensions of
DOI
10.3906/kim-1910-35
Keywords
Hyperbranched polymer, poly(aminoester), nanoparticle, drug delivery, 5-fluorouracil
First Page
518
Last Page
534
Recommended Citation
ÖZTÜRK, A. B, OĞUZ, N, ŞAHİN, H. T, EMİK, S, & ALARÇİN, E (2020). Design of an amphiphilic hyperbranched core/shell-type polymeric nanocarrier platform for drug delivery. Turkish Journal of Chemistry 44 (2): 518-534. https://doi.org/10.3906/kim-1910-35