A convenient and efficient method has emerged for the one-pot synthesis of substituted quinazolin-4(3$H)$-ones and nonaromatic alkaloids. 2-Substituted quinazolin-4(3H)-ones, 2,3-disubstituted quinazolin-4(3$H)$-ones, and 2,3-dihydroquinazolin-4(1$H)$-ones were obtained at yields of 46% to 95% by a one-pot reaction of $N$-(2-aminobenzoyl) benzotriazoles with amines and orthoesters or aldehydes under catalyst-free conditions.
Benzotriazole, $N$-(2-aminobenzoyl)benzotriazole, quinazolin-4(3$H)$-one, 2, 3-dihydroquinazolin-4(1$H)$-one, 2-substituted quinazolin-4(3$H)$-one
ŞENOL, İLBİLGE MERVE; ÇELİK, İLHAMİ; and AVAN, İLKER
"One-pot synthesis of quinazolin-4(3$H$)-ones and 2,3-dihydroquinazolin-4(1$H$)-ones utilizing $N$-(2-aminobenzoyl)benzotriazoles,"
Turkish Journal of Chemistry: Vol. 43:
6, Article 6.
Available at: https://journals.tubitak.gov.tr/chem/vol43/iss6/6