Turkish Journal of Chemistry
Abstract
The nanostructuring of hydroxyl-substituted diazacrown-ether (DC) by silver nanoparticles was obtained by green synthesis method in order to increase the antibacterial activity of silver nanoparticles. The synthesized DC, nanoparticles, and nanosupramolecular complex (Ag@DC) were studied by TEM, powder-XRD, and NMR, IR, and UV spectroscopy methods. The Ag@DC nanostructures were uniform and their sizes ranged from 8 to 18 nm. IR and UV spectra revealed the noncovalent formation of the nanosupramolecular complex. The antibacterial activities of the prepared active agents were investigated on gram-positive and gram-negative bacteria by twofold microdilution method. Ultrastructural study by TEM was performed on \textit{E. coli} BDU12 after treatment with Ag@DC. The results showed the improvement of the antibacterial action of Ag@DC compared to silver nanoparticles (E. coli BDU12 - 32 times, A. baumannii BDU32 - 16 times, K. pneumoniae BDU44 and P. aeruginosa BDU49 - 4 times, S. aureus BDU23 - 512 times). Chelating by DC significantly improved the antibacterial effects of the silver nanoparticles on gram-positive and gram-negative bacteria due to the ionophoric behavior of the crown ethers.
DOI
10.3906/kim-1907-10
Keywords
Silver nanoparticles, diazacrown ether, transmission electron microscopy, ultrastructural microscopy, antibacterial activity
First Page
1711
Last Page
1721
Recommended Citation
HAJIYEVA, SARVINAZ; HASANOVA, ULVIYYA; GAKHRAMANOVA, ZAREMA; ISRAYILOVA, AYGUN; GANBAROV, KHUDAVERDI; GASIMOV, ELDAR; RZAYEV, FUAD; EYVAZOVA, GONCHA; HUSEYNZADA, ALAKBAR; ALIYEVA, GUNEL; HASANOVA, ILAHA; and MAHARRAMOV, ABEL
(2019)
"The role of diazacrown ether in the enhancement of the biological activity of silver nanoparticles,"
Turkish Journal of Chemistry: Vol. 43:
No.
6, Article 16.
https://doi.org/10.3906/kim-1907-10
Available at:
https://journals.tubitak.gov.tr/chem/vol43/iss6/16
