Synthesis and bioactivity of sulfide derivatives containing 1,3,4-oxadiazole and pyridine

Authors

GANG YU
SHUNHONG CHEN
FENG HE
DEXIA LUO
YU ZHANG
JIAN WU

DOI

10.3906/kim-1901-45

Abstract

A series of novel sulfide derivatives containing 1,3,4-oxadiazole and pyridine were synthesized, characterized, and tested for their antibacterial activity against tobacco bacterial wilt and rice bacterial blight and for insecticidal activity toward diamondback moth. The results showed that some compounds had good insecticidal and bactericidal activity, e.g., the activities of compounds 6e and 6g-6j toward tobacco bacterial wilt were much better than those of commercial thiodiazole-copper, and some of the synthesized compounds possessed good insecticidal activity against Plutella xylostella. Compounds 6d, 6h, 6j, 6l, 6p, 6r, and 6p displayed over 93% activity at 500 mg L$^{-1}$.

Keywords

Sulfide derivative, 1, 3, 4-oxadiazole, pyridine, synthesis, antibacterial activity, insecticidal activity

First Page

1075

Last Page

1085

Recommended Citation

YU, GANG; CHEN, SHUNHONG; HE, FENG; LUO, DEXIA; ZHANG, YU; and WU, JIAN (2019) "Synthesis and bioactivity of sulfide derivatives containing 1,3,4-oxadiazole and pyridine," Turkish Journal of Chemistry: Vol. 43: No. 4, Article 8. https://doi.org/10.3906/kim-1901-45
Available at: https://journals.tubitak.gov.tr/chem/vol43/iss4/8