Synthesis of some ketones via nano-nickel oxide catalyzed acylation of arylzinc reagents; strategy involving the use of mixed (methyl)(aryl)zincs

Authors

ÖZGEN ÖMÜR PEKEL
ENDER ERDİK
MELİKE KALKAN

DOI

10.3906/kim-1712-28

Abstract

Nano-NiO catalyzed acylation of mixed (methyl)(aryl)zincs with aromatic acyl halides in THF at room temperature provides a new facile route for aryl-aroyl coupling. Among NiCl$_{2}$.L$_{2}$ and NiCl$_{2}$.L (L = monodentate and bidentate phosphine ligand) catalysts, the lower catalyst loading of NiCl$_{2}$ (dppf) may seem attractive; however, nano-NiO, being the lowest cost catalyst, is more favorable for aroylation of (methyl)(aryl)zincs. This procedure also provides a supplement to Cu and Pd catalyzed acylation of diorganozincs.

Keywords

Mixed diorganozincs, acylation, nickel catalyst, group selectivity

First Page

759

Last Page

767

Recommended Citation

PEKEL, ÖZGEN ÖMÜR; ERDİK, ENDER; and KALKAN, MELİKE (2018) "Synthesis of some ketones via nano-nickel oxide catalyzed acylation of arylzinc reagents; strategy involving the use of mixed (methyl)(aryl)zincs," Turkish Journal of Chemistry: Vol. 42: No. 3, Article 13. https://doi.org/10.3906/kim-1712-28
Available at: https://journals.tubitak.gov.tr/chem/vol42/iss3/13