Aliphatic nitroalkanes with different functional groups were synthesized from the Michael addition reactions of active methylene compounds 2 and nitrovinyl arenes 1 in high yields. The synthesized Michael adducts were subjected to intramolecular cyclization to give heteroaryl substituted γ-lactams in good to high yields under mild reaction conditions.
ÇINAR, SEDA and ÜNALEROĞLU, CANAN
"Facile synthesis of heteroaryl substituted -lactams from nitrovinyl arenes,"
Turkish Journal of Chemistry: Vol. 42:
1, Article 3.
Available at: https://journals.tubitak.gov.tr/chem/vol42/iss1/3