Copper/periodic mesoporous organosilica (Cu/PMO) nanocomposites provided a highly active, reusable, globular, solid-phase catalyst for click chemistry. The reaction proceeds by mixing organohalides, sodium azide, alkyne, and the catalyst in an aqueous medium to afford the desired products. The cost efficiency and recyclability of the catalyst up to six runs without appreciable loss of activity and high yields of products make this procedure greener.
NEJADSHAFIEE, VAJIHE and NAEIMI, HOSSEIN
"Nanocomposite copper metal as an efficient heterogeneous catalyst in click synthesis of 1,2,3-triazoles in aqueous media,"
Turkish Journal of Chemistry: Vol. 41:
5, Article 8.
Available at: https://journals.tubitak.gov.tr/chem/vol41/iss5/8