Turkish Journal of Chemistry
Abstract
A series of novel 2,5-dioxopyrrolidines were synthesized by the one-pot reaction of coumarin-3-carboxylic acids 1 with thiourea derivatives and alkyl isocyanides in the presence of Fe$_{3}$O$_{4}$ NPs @ lipase as heterogeneous reusable nanobiocatalysts with high yields.
DOI
10.3906/kim-1612-45
Keywords
Diastereoselective synthesis, 2, 5-dioxopyrrolidine derivatives, biocatalytic reactions
First Page
502
Last Page
513
Recommended Citation
MOHAJER, S, & BAHARFAR, R (2017). Diastereoselective synthesis of novel 2,5-dioxopyrrolidine derivatives via biocatalytic domino reactions. Turkish Journal of Chemistry 41 (4): 502-513. https://doi.org/10.3906/kim-1612-45