Turkish Journal of Chemistry
Graphite oxide catalyzed synthesis of $\beta $-amino alcohols by ring-opening of epoxides
Graphite oxide as a heterogeneous and recyclable solid acid catalyzed a simple and efficient method for the synthesis of $\beta $-amino alcohols by ring opening of epoxides with amines. This method is effective with various aromatic and aliphatic amines under solvent-free conditions. The corresponding $\beta $-amino alcohols are obtained in high yields (56%-95%) and short reaction times (15-30 min) with high regio- and chemoselectivity under metal-free conditions.
Ring opening, epoxides, amines, $\beta $-amino alcohols, graphite oxide, metal-free conditions
MIRZA-AGHAYAN, MARYAM; ALVANDI, FARZANEH; TAVANA, MAHDIEH MOLAEE; and BOUKHERROUB, RABAH
"Graphite oxide catalyzed synthesis of $\beta $-amino alcohols by ring-opening of epoxides,"
Turkish Journal of Chemistry: Vol. 41:
1, Article 6.
Available at: https://journals.tubitak.gov.tr/chem/vol41/iss1/6