Characterization of an Al$^{3+}$-selective fluorescent probe based on a benzoyl hydrazine derivative and its application in cell imaging

Authors

YUXIANG JI
CHUNWEI YU
SHAOBAI WEN
JUN ZHANG

DOI

10.3906/kim-1511-37

Abstract

A fluorescent probe based on benzoyl hydrazine was synthesized and characterized as an Al$^{3+}$-selective fluorescent probe. This probe showed good selectivity towards Al$^{3+\, }$compared to other common ions. Under optimized experimental conditions, the probe exhibited a linear dynamic response for Al$^{3+}$ from 5.0 $\times $ 10$^{-7}$ to 4.5 $\times $ 10$^{-6}$ M with a detection limit of 1.3 $\times $ 10$^{-7}$ M in ethanol-water solution (9:1, v:v, pH 6.8, 20 mM HEPES). Furthermore, it was used for imaging of Al$^{3+}$ in living cells with satisfying results.

Keywords

Fluorescent probes, Al$^{3+}$, cell imaging

First Page

625

Last Page

630

Recommended Citation

JI, YUXIANG; YU, CHUNWEI; WEN, SHAOBAI; and ZHANG, JUN (2016) "Characterization of an Al$^{3+}$-selective fluorescent probe based on a benzoyl hydrazine derivative and its application in cell imaging," Turkish Journal of Chemistry: Vol. 40: No. 4, Article 8. https://doi.org/10.3906/kim-1511-37
Available at: https://journals.tubitak.gov.tr/chem/vol40/iss4/8