Turkish Journal of Chemistry
Abstract
Novel chiral bisoxazoline ligands based on norbornadiene were synthesized and used for the asymmetric Henry reaction. Various aromatic aldehydes were converted into chiral $\beta $-nitro alcohols with high yields and moderate to acceptable enantioselectivities under the optimized reaction conditions.
DOI
10.3906/kim-1504-80
Keywords
Asymmetric synthesis, Henry reaction, chiral bisoxazolines, nitroaldol, copper
First Page
248
Last Page
261
Recommended Citation
DELİKUŞ, R, ÇAKIR, E, DEMİREL, N, BALCI, M, & KARATAŞ, B (2016). Synthesis of novel chiral bisoxazoline ligands with a norbornadiene backbone: use in the copper-catalyzed enantioselective Henry reaction. Turkish Journal of Chemistry 40 (2): 248-261. https://doi.org/10.3906/kim-1504-80
