Turkish Journal of Chemistry
Wittig--Horner reagents: powerful tools in the synthesis of 5-and 6-heterocyclic compounds; shedding light on their application in pharmaceutical chemistry
This paper reviews literature over 25 years' activity on phosphoryl carbanion reagents and shows that these compounds are powerful tools in organic chemistry. The main target of this review is to outline some of the reactive peculiarities that make this class of compounds powerful tools in the synthesis of 5- and 6-heterocyclic compounds and/or substituted heterocycle phosphor esters. The importance of these latter compounds in pharmacology is also discussed.
Phosphonyl carbanions reagents, phospha-Michael (P-Michael) addition, Perkin-type reaction, five-membered heterocycles, six-membered heterocycles, nucleophiles
KHIDRE, RIZK ELSAYED and ABDOU, WAFAA MAHMOUD
"Wittig--Horner reagents: powerful tools in the synthesis of 5-and 6-heterocyclic compounds; shedding light on their application in pharmaceutical chemistry,"
Turkish Journal of Chemistry: Vol. 40:
2, Article 2.
Available at: https://journals.tubitak.gov.tr/chem/vol40/iss2/2