Turkish Journal of Chemistry
Abstract
A green and efficient protocol has been developed for the Pd(OAc)$_{2}$-catalyzed ligand-free Suzuki--Miyaura reaction of $N$-methyliminodiacetic acid (MIDA) boronates in water. In the presence of Pd(OAc)$_{2}$ as a catalyst and ($i$-Pr)$_{2}$NH as a base, the cross-coupling reactions of aryl bromides with aryl MIDA boronates proceeded smoothly in water without any surfactant, and various functional groups were tolerated under the optimized conditions.
DOI
10.3906/kim-1505-97
Keywords
Palladium, ligand-free, Suzuki--Miyaura reaction, $N$-methyliminodiacetic acid boronates, water
First Page
1208
Last Page
1215
Recommended Citation
LIU, C, LI, X, WANG, X, & QIU, J (2015). Palladium-catalyzed ligand-free and efficient Suzuki--Miyaura reaction of $N$-methyliminodiacetic acid boronates in water. Turkish Journal of Chemistry 39 (6): 1208-1215. https://doi.org/10.3906/kim-1505-97
