Turkish Journal of Chemistry
Article Title
DOI
10.3906/kim-1505-97
Abstract
A green and efficient protocol has been developed for the Pd(OAc)$_{2}$-catalyzed ligand-free Suzuki--Miyaura reaction of $N$-methyliminodiacetic acid (MIDA) boronates in water. In the presence of Pd(OAc)$_{2}$ as a catalyst and ($i$-Pr)$_{2}$NH as a base, the cross-coupling reactions of aryl bromides with aryl MIDA boronates proceeded smoothly in water without any surfactant, and various functional groups were tolerated under the optimized conditions.
Keywords
Palladium, ligand-free, Suzuki--Miyaura reaction, $N$-methyliminodiacetic acid boronates, water
First Page
1208
Last Page
1215
Recommended Citation
LIU, CHUN; LI, XINMIN; WANG, XINNAN; and QIU, JIESHAN
(2015)
"Palladium-catalyzed ligand-free and efficient Suzuki--Miyaura reaction of $N$-methyliminodiacetic acid boronates in water,"
Turkish Journal of Chemistry: Vol. 39:
No.
6, Article 7.
https://doi.org/10.3906/kim-1505-97
Available at:
https://journals.tubitak.gov.tr/chem/vol39/iss6/7
