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Turkish Journal of Chemistry

Abstract

We have developed a simple synthetic methodology for bis-spirocycles and spiroindole derivatives starting with a commercially available 6-bromo-2-tetralone. Here, we have used Fischer indolization, ring-closing metathesis, and Suzuki--Miyaura cross-coupling as key steps to assemble a variety of spirocyclic frameworks. The methodology developed here is simple and it may be useful to prepare various spirocycles containing indole moiety.

DOI

10.3906/kim-1502-116

Keywords

Spirocycles, Fischer indolization, ring-closing metathesis, Suzuki coupling, Grubbs' catalyst

First Page

1190

Last Page

1198

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