In this account the authors' latest results in C-C coupling catalysis are reviewed. First, an efficient catalytic system for the Kumada-Tamao-Corriu coupling reaction based on NHC-phosphine (NHC = N-heterocyclic carbene) nickel complexes is presented. Then the use of palladium complexes of chiral ferrocenyl NHC-phosphines in the asymmetric Suzuki-Miyaura coupling reaction is reported. High catalytic activities and moderate enantioselectivities (ee up to 46%) were obtained. Chiral ferrocenyl phosphine-ethers were also tested in the asymmetric Suzuki-Miyaura reaction yielding good activities and moderate enantioselectivities (ee up to 37%). Finally, the original synthesis of a ferrocenyl rhodium(III) complex and its successful use as catalyst for a C-C coupling reaction via C-H activation of 2-phenylpyridine is presented.
LABANDE, AGNES; DEYDIER, ERIC; MANOURY, ERIC; DARAN, JEAN-CLAUDE; AUDIN, CATHERINE; and POLI, RINALDO
"Contribution of heterobifunctional ligands to transition metal-catalysed C--C coupling reactions,"
Turkish Journal of Chemistry: Vol. 39:
6, Article 2.
Available at: https://journals.tubitak.gov.tr/chem/vol39/iss6/2