New tetrazolic azo dyes linked to (thio)barbiturate and electron-rich aromatics as potential antimicrobial agents

Authors

NADER NOROOZI PESYAN
DAVOUD SOLEIMANI
NIMA HOSSEINI JAZANI

DOI

10.3906/kim-1412-46

Abstract

A series of new tetrazolic azo dyes based on (thio)barbiturate and electron-rich aromatics were synthesized in excellent yield. The electron-donor and tetrazole ring moieties were linked by a $p$-phenylazo bridge and the structural characterizations were achieved by FT IR, $^{1}$H and $^{13}$C NMR, and UV-visible spectrometry. The antibacterial activity of the synthesized compounds was tested against gram-positive and gram-negative bacterial strains, namely \textit{Acinetobacter calcoaceticus} (ATCC23055), \textit{Escherichia coli} (ATCC2592), \textit{Pseudomonas aeruginosa} (ATCC27853), and \textit{Staphylococcus aureus} (ATCC25923). As a result, potential antimicrobial effects were seen for some of the synthesized compounds.

Keywords

Tetrazole, azo dye, (thio)barbituric acid, antimicrobial effect

First Page

998

Last Page

1011

Recommended Citation

PESYAN, NADER NOROOZI; SOLEIMANI, DAVOUD; and JAZANI, NIMA HOSSEINI (2015) "New tetrazolic azo dyes linked to (thio)barbiturate and electron-rich aromatics as potential antimicrobial agents," Turkish Journal of Chemistry: Vol. 39: No. 5, Article 8. https://doi.org/10.3906/kim-1412-46
Available at: https://journals.tubitak.gov.tr/chem/vol39/iss5/8